James Edward Rothman

Curriculum vitae

King Faisal International Prize in Science (with G. Blobel and H. Pelham),                                                         Saudia Arabia                                                                                                          1996

The Harden Medal , U.K.                                                                                            1997

The Lounsbery Award, National Academy of Sciences , U.S.A.                              1997

The Feodor Lynen Award (with G. Blobel and G. Schatz), U.S.A.                                     1997

Dr. h.c., University of Geneva , Switzerland                                                                         1997

The Jacobæus Prize, Denmark                                                                                   1999

The Heineken Prize, The Netherlands                                                                      2000

The Otto-Warburg Medal, Germany                                                                                    2001

The Louisa Gross Horwitz Prize (with R. Schekman), U.S.A.                                 2002

The Lasker Basic Research Award (with R. Schekman), U.S.A.                             2002

Honorary Member, Japanese Biochemical Society                                                  2005

Lectureships:

Lamport Visiting Professor, Columbia College of

   Physicians and Surgeons                                                                                        1985

Welch Foundation Lecturer, State of Texas                                                              1987

Wellcome Foundation Lecturer, F.A.S.E.B.                                                              1988

Proctor Lectureship in Life Sciences, University of Illinois                                       1989

Mayer Lecturer, Massachusetts Institute of Technology                                         1989

Japan Society for the Promotion of Science                                                              1990

Albert Claude Lecture, European Society for Cell Biology                                      1990

Utter Lecture, Case Western Reserve School of Medicine                                       1990

The Harvey Lectures                                                                                                  1991

Nordic Molecular Biology Association Lecture                                                        1992

Gavin Borden Lecture, British Society for Cell and

   Developmental Biology                                                                                           1993

Crane Lecture, Rutgers Medical School                                                                    1993

Hille Lecture in Neuroscience, Univ. of Washington                                                            1994

Lehninger Lecture, Johns Hopkins University                                                         

   School of Medicine                                                                                                   1994

Garland Lecture, University of Dundee                                                                    1995

Baird Hastings Lecture, Harvard Medical School                                                     1995

Grass Foundation Distinguished Lecture, Society of          

   Neuroscience                                                                                                           1995

Distinguished Scientist Lectures, Bard College                                                         1995

Steenbock Lectures, Univ. of Wisconsin-Madison                                                    1996

Hoppe-Seyler Lecture, German Biochemical Society                                                           1996

The Weizmann Memorial Lectures, Weizmann Institute, Israel                              1996

Von Neumann Memorial Lectures, The Institute   

   for Advanced Study                                                                                                           1996

Cruickshank Lecturer, Gordon Research Conference                                             1997

The Jubilee Lecture, British Biochemical Society                                                      1997

Samuel Rudin Distinguished Visiting Professor, Columbia

University College of Physicians and Surgeons                                                       1998

Life Sciences Lecturer, University of Michigan                                                        2000

Beering Award for Advancement of Biomedical Science,

  Indiana University School of Medicine                                                                  2005

Honorary Professor, Peking Union Medical College , Beijing , China                      2005

Q. R. Murphy Lecture in Physiology, University of Wisconsin                              2005

Activities:

Editorial Board, Molecular and Cellular Biology                                                     1982 ‑ 1984

Chairman, Gordon Conference on Molecular Membrane Biology                         1983

Board of Editors, Science                                                                                           1984 ‑ 1989

Editorial Committee, Annual Review of Biochemistry                                            1985 ‑ 1990

Editorial Board, Cell                                                                                                  1984 ‑ 1994

NIH Study Section, Molecular Cytology                                                                  1990 ‑ 1994

Council, National Institute of Digestive and Kidney Diseases, NIH                                   1997 - 1999

Developmental Therapeutics Review Group, National Cancer Institute               1997 - 1998

Board of Senior Editors, Journal of Clinical Investigation                                       2002 -

Associate Editor, Annual Review of Biochemistry                                                  2003 –

PUBLICATIONS

JAMES EDWARD ROTHMAN

 1.        Rothman, J.E., Melchior, D.L., and Morowitz, H.J.  1972.  A  dilatometer for volume‑temperature determinations of liquids.  Rev. Sci. Instr.  43:743‑745.

 2.        Rothman, J.E. and Engelman, D.M.  1972.  Molecular mechanism for the interaction of phospholipid with cholesterol.  Nature ( London ) New Biology  237:42‑44.

 3.        Engelman, D.M. and Rothman, J.E.  1972.  The planar organization of lecithin‑cholesterol bilayers.  J. Biol. Chem.  247:3694‑3697.

 4.        Rothman, J.E.  1973.  The molecular basis of mesomorphic phase transitions in phospholipid systems.  J. Theoret. Biol.  38:1‑16.

 5.        Rothman, J.E. and Dawidowicz, E.A.  1975.  Asymmetric exchange of vesicle phospholipids catalyzed by the phosphatidylcholine exchange protein:  Measurement of inside‑outside transitions.  Biochemistry  14:2809‑2816.

 6.        Rothman, J.E., Tsai, D.K., Dawidowicz, E.A., and Lenard, J.  1976.  Transbilayer phospholipid asymmetry and its maintenance in the membrane of influenza virus.  Biochemistry  15:2361‑2370.

 7.        Lenard, J. and Rothman, J.E.  1976.  Transbilayer distribution and movement of cholesterol and phospholipid in the membrane of influenza virus.  Proc. Natl. Acad. Sci. USA  73:391‑395.

 8.        Dawidowicz, E.A. and Rothman, J.E.  1976.  Fusion and protein‑mediated    phospholipid exchange studied with single bilayer phosphatidylcholine vesicles of different density.  Biochem. Biophys. Acta  455:621‑630.

 9.        Rothman, J.E. and Kennedy, E.P.  1977.  Asymmetrical distribution of phospholipids in the membrane of Bacillus megaterium.  J. Molec. Biol.  110:603‑618.

10.       Rothman, J.E. and Kennedy, E.P.  1977.  Rapid transmembrane movement of  newly synthesized phospholipids during membrane assembly.  Proc. Natl. Acad. Sci. USA 74:1821‑1825.

11.       Rothman, J.E. and Lenard, J.  1977.  Membrane asymmetry:  The nature of membrane asymmetry provides clues to the puzzle of how membranes are assembled.  Science 195:743‑753.

12.       Katz, F.N., Rothman, J.E., Lingappa, V.R., Blobel, G., and Lodish, H.F.    1977.  Membrane assembly in vitro:  Synthesis, glycosylation and asymmetric insertion of a transmembrane protein.  Proc. Natl. Acad. Sci. USA  74:3278‑3282.

13.       Katz, F.N., Rothman, J.E., Knipe, D.M., and Lodish, H.F.  1977.  Membrane  assembly:  Synthesis and intracellular processing of the vesicular stomatitis viral glycoprotein.  ICN‑UCLA Symposium Proc.:  J. Supramol. Struct.  7:353-370.

14.       Rothman, J.E. and Lodish, H.F.  1977.  Synchronised transmembrane insertion and glycosylation of a nascent membrane protein.  Nature ( London ) 269:775‑780.

15.       Rothman, J.E., Katz, F. N., and Lodish, H.F.  1978.  Glycosylation of a membrane protein is restricted to the growing polypeptide chain but is not necessary for insertion as a transmembrane protein.  Cell  15:1447‑1454.

16.       Lodish, H.F. and Rothman, J.E.  l979.  The assembly of cell membranes.  Sci. Amer. 240:48‑63.

17.       Rothman, J.E.  1980.  An overview of membrane structure and biosynthesis.  In: Membrane‑Membrane Interactions – Symp. of the Soc. of General Physiologists.  Gilula, N.B. (ed.), Raven Press, 34:1‑9. 

18.       Rothman, J.E. and Fine, R.E.  1980.  Coated vesicles transport newly synthesized membrane glycoproteins from the endoplasmic reticulum to plasma membrane in two successive stages.  Proc. Natl. Acad. Sci. USA  77:780‑784.

19.       Rothman, J.E., Bursztyn‑Pettegrew, H., and Fine, R.E.  1980.  Transport of the membrane glycoprotein of vesicular stomatitis virus to the cell surface in two stages by clathrin­coated vesicles.  J. Cell Biol.  86:162‑171.

20.       Fries, E. and Rothman, J.E.  1980.  Transport of vesicular stomatitis virus glycoprotein in a cell‑free extract.  Proc. Natl. Acad. Sci. USA  77:3870‑3874.

21.       Rothman, J.E. and Fries, E.  1981.  Transport of newly synthesized   vesicular stomatitis viral glycoprotein to purified Golgi membranes.  J. Cell Biol.  89:162‑168.

22.       Rubenstein, J.L.R., Fine, R.E., Luskey, B.D., and Rothman, J.E.  1981.  Purification of coated vesicles by agarose gel electrophoresis.  J. Cell Biol.  89:357‑361.

23.       Fries, E. and Rothman, J.E.  1981.  Transient activity of Golgi‑like membranes as donors of vesicular stomatitis viral glycoprotein in vitro.  J. Cell Biol.  90:697‑704.

24.       Rothman, J.E.  1981.  The Golgi apparatus:  Two organelles in tandem.  Science 213:1212‑1219.

25.       Dunphy, W.G., Fries, E., Urbani, L.J., and Rothman, J.E.  1981.  Early and late functions associated with the Golgi apparatus reside in distinct compartments.  Proc. Natl. Acad. Sci. USA  78:7453‑7457.

26.       Schmid, S.F., Matsumoto, A.K., and Rothman, J.E.  1982.  A domain of clathrin that forms coats.  Proc. Natl. Acad. Sci. USA  79:91‑95.

27.       Patzer, E.J., Schlossman, D.M., and Rothman, J.E.  1982.  Release of clathrin from coated vesicles dependent upon a nucleoside triphosphate and a cytosol fraction.  J. Cell Biol. 93:230‑236.

28.       Rothman, J.E., Fries, E., Dunphy, W.G., and Urbani, L.J.  1982.  The Golgi apparatus, coated vesicles, and the sorting problem.  Cold Spring Harbor Symposium on Quantitative Biology  46:797‑805.

29.       Rothman, J.E.  1982.  The Golgi apparatus:  Roles for distinct ‘cis’ and ‘trans’ compartments.  In:  CIBA Foundation Symp. on “Membrane Recycling” 92:120‑137.

30.       Rothman, J.E.  1983.  Internal membranes and the synthesis of macromolecules.  In:  Molecular Biology of the Cell, Chapter 7.    Alberts, B., Bray, D., Lewis, J., Porter, K., Raff, M., Roberts, K., and Watson, J.D. (eds.), Garland Press, NY.

31.       Balch, W.E., Fries, E., Dunphy, W.G., Urbani, L.J., and Rothman, J.E.  1983.  Transport‑coupled oligosaccharide processing in a cell‑free system.  Meth. Enzymol. 98:37‑47.

32.       Dunphy, W.G. and Rothman, J.E.  1983.  Compartmentation of asparagine‑linked oligosaccharide processing in the Golgi apparatus.  J. Cell Biol.  97:270‑275.

33.       Schlossman, D.M., Schmid, S.L., Braell, W.A., and Rothman, J.E.  1984.  An enzyme that removes clathrin coats:  Purification of an uncoating ATPase.  J. Cell Biol.  99:723‑733.

34.       Braell, W.A., Schlossman, D.M., Schmid, S.L., and Rothman, J.E.  1984.    Dissociation of clathrin coats coupled to the hydrolysis of ATP:  Role of an uncoating ATPase.  J.  Cell Biol.  99:734‑741.

35.       Rothman, J.E., Urbani, L.H., and Brands, R.  1984.  Transport of protein between cytoplasmic membranes of fused cells:  Correspondence to processes reconstituted in a cell‑free system.  J. Cell Biol.  99:248‑259.

36.       Rothman, J.E., Miller, R.L., and Urbani, L.J.  1984.  Intercompartmental transport in the Golgi complex is a dissociative process:  Facile transfer of membrane protein between two Golgi populations.  J. Cell Biol.  99:260‑271.

37.       Balch, W.E., Dunphy, W.G., Braell, W.A., and Rothman, J.E.  1984.    Reconstitution of the transport of protein between successive compartments of the Golgi measured by the coupled incorporation of N‑acetylglucosamine.  Cell  39:405‑416.

38.       Braell, W.A., Balch, W.E., Dobbertin , D.C. , and Rothman, J.E.  1984.  The  glycoprotein that is transported between successive compartments of the Golgi in a cell‑free system resides in stacks of cisternae.  Cell  39:511‑524.

39.       Balch, W.E., Glick, B.S., and Rothman, J.E.  1984.  Sequential intermediates in the pathway of intercompartmental transport in a cell‑free system.  Cell  39:525‑536.

40.       Schmid, S.L., Braell, W.A., Schlossman, D.M., and Rothman, J.E.  1984.  A role for clathrin light chains in the recognition of clathrin cages by ‘uncoating ATPase.’  Nature 311:228‑231.

41.       Rothman, J.E. and Lenard, J.  1984.  Membrane traffic in animal cells.  Trends Biochem. Sci.  9:176‑178.

42.       Dunphy, W.G., Brands, R., and Rothman, J.E.  1985.  Attachment of terminal N‑acetyl­glucosamine to asparagine‑linked oligosaccharides occurs in central cisternae of the Golgi stack.  Cell  40:463‑472.

43.       Hino, Y. and Rothman, J.E.  1985.  Glucosidase II, a glycoprotein of the  endoplasmic reticulum membrane.  Proteolytic cleavage into enzymatically active fragments.  Biochemistry  24:800‑805.

44.       Balch, W.E. and Rothman, J.E.  1985.  Characterization of protein transport between successive compartments of the Golgi apparatus: Asymmetric property of donor and acceptor activities in a cell-free system.  Arch. Biochem. Biophys.  240:413‑425.

45.       Schmid, S.L. and Rothman, J.E.  1985.  Enzymatic dissociation of clathrin cages in a two- stage process.  J. Biol. Chem.  260:10044‑10049.

46.       Schmid, S.L. and Rothman, J.E.  1985.  Two classes of binding sites for uncoating protein in clathrin triskelions.  J. Biol. Chem.  260:10050‑10056.

47.       Schmid, S.L., Braell, W.A., and Rothman, J.E.  1985.  ATP catalyzes the sequestration of clathrin during enzymatic uncoating.  J. Biol. Chem.  260:10057‑10062.

48.       Dunphy, W.G. and Rothman, J.E.  1985.  Compartmental organization of the Golgi stack.  Cell  42:13‑21.

49.       Rothman, J.E.  1985.  The compartmental organization of the Golgi apparatus.  Sci. Amer.  253:74‑89.

50.       Brands, R., Snider, M.D., Hino, Y., Park, S.S., Gelboin, H., and Rothman, J.E.  1985.  Retention of membrane proteins by the endoplasmic reticulum.  J. Cell Biol.  101:1724‑1732.

51.       Wattenberg, B.W., Balch, W.E., and Rothman, J.E.  1986.  A novel prefusion complex formed during protein transport between Golgi cisternae in a cell‑free system.  J. Biol. Chem.  261:2202‑2207.

52.       Wattenberg, B.W. and Rothman, J.E.  1986.  Multiple cytosolic components  promote intra‑Golgi protein transport.  Resolution of a protein acting at a late stage, prior to membrane fusion.  J. Biol. Chem.  261:2208‑2213.

53.       Rothman, J.E. and Schmid, S.L.  1986.  Enzymatic recycling of clathrin from coated vesicles.  Cell  46:5‑9.

54.       Chappell, T.G., Welch, W.F., Schlossman, D.M., Palter, K.B., Schlesinger, M.J., and Rothman, J.E.  1986.  Uncoating ATPase is a member of the 70 kilodalton family of stress proteins.  Cell  45:3‑13.

55.       Paquet, M.R., Pfeffer, S.R., Burczak, J.D., Glick, B.S., and Rothman, J.E.  1986.  Components responsible for transport between successive Golgi cisternae are highly conserved in evolution.  J. Biol. Chem.  261:4367‑4370.

56.       Dunphy, W.G., Pfeffer, S.R., Clary, D.O., Wattenberg, B.W., Glick, B.S., and Rothman, J.E.  1986.  Yeast and mammals utilize similar cytosolic components to drive protein transport through the Golgi complex.  Proc. Natl. Acad. Sci. USA  83:1622‑1626.

57.       Orci, L., Glick, B.S., and Rothman, J.E.  1986.  A new type of coated vesicular carrier that appears not to contain clathrin:  Its possible role in protein transport within the Golgi stack.  Cell  46:171‑184.

58.       Rothman, J.E. and Kornberg, R.D.  1986.  Cell biology: An unfolding story of protein translocation.  Nature  322:209‑210.

59.       Glick, B.S. and Rothman, J.E.  1987.  A possible role for acyl‑coenzyme A in intracellular protein transport.  Nature  326:309‑312.

60.       Chappell, T.G., Konforti, B.B., Schmid, S.L., and Rothman, J.E.  1987.  The ATPase core of a clathrin uncoating protein.  J. Biol. Chem.  262:746‑751.

61.       Wieland, F.T., Gleason, M.L., Serafini, T.A., and Rothman, J.E.  1987.     The rate of bulk flow from the endoplasmic reticulum to the cell surface.  Cell  50:289‑300.

62.       Rothman, J.E.  1987.  Protein sorting by selective retention in the endoplasmic reticulum and Golgi stack.  Cell  50:521‑522.

63.       Rothman, J.E.  1987.  Transport of the vesicular stomatitis glycoprotein to trans Golgi membranes in a cell‑free system.  J. Biol. Chem.  262:12502‑12510.

64.       Pfeffer, S.R. and Rothman, J.E.  1987.  Biosynthetic protein transport and sorting by the endoplasmic reticulum and Golgi.  Ann. Rev. Biochem.  56:829‑852.

65.       Melançon, P., Glick, B.S., Malhotra, V., Weidman, P.J., Serafini, T., Gleason, M.L., Orci, L., and Rothman, J.E.  1987.  Involvement of GTP‑binding “G” proteins in transport through the Golgi stack.  Cell  51:1053‑1062.

66.       Malhotra, V., Orci, L., Glick, B.S., Block, M.R., and Rothman, J.E.  1988.  Role of an N‑ethylmaleimide-sensitive transport component in promoting fusion of transport vesicles with cisternae of the Golgi stack.  Cell  54:221‑227.

67.       Block, M.R., Glick, B.S., Wilcox , C.A. , Wieland, F.T., and Rothman, J.E.  1988.  Purification of an N‑ethylmaleimide-sensitive protein catalyzing vesicular transport.  Proc. Natl. Acad. Sci. USA  85:7852‑7856.

68.       Orci, L., Malhotra, V., Amherdt, M., Serafini, T., and Rothman, J.E.  1989.  Dissection of a single round of vesicular transport:  Sequential intermediates for intercisternal movement in the Golgi stack.  Cell  56:357‑368.

69.       Weidman, P.J., Melançon, P., Block, M.R., and Rothman, J.E.  1989.  Binding of an N‑ethylmaleimide-sensitive fusion protein to Golgi membranes requires both a soluble protein(s) and an integral membrane receptor.  J. Cell Biol.  108:1589-1596.

70.       Malhotra, V., Serafini, T., Orci, L., Shepherd, J.C., and Rothman, J.E.  1989.  Purification of a novel class of coated vesicles mediating biosynthetic protein transport through the Golgi stack.  Cell  58:329‑336.

71.       Diaz, R., Mayorga, L.S., Weidman, P.J., Rothman, J.E., and Stahl, P.D.  1989.  Vesicle fusion following receptor‑mediated endocytosis requires a protein active in Golgi transport.  Nature  339:398‑400.

72.       Beckers, C.J.M., Block, M.R., Glick, B.S., Rothman, J.E., and Balch, W.E.  1989.  Vesicular transport between the endoplasmic reticulum and the Golgi stack requires the NEM-sensitive fusion protein.  Nature  339:397-398.

73.       Wilson , D.W., Wilcox , C.A. , Flynn, G.C., Chen, E., Kuang, W.J., Henzel, W.J., Block, M.R., Ullrich, A., and Rothman, J.E.  1989.  A fusion protein required for vesicle-mediated transport in both mammalian cells and yeast.  Nature  339:355‑359.

74.       Flynn, G.C., Chappell, T.G., and Rothman, J.E.  1989.  Peptide binding and release by proteins implicated as catalysts of protein assembly.  Science  245:385‑390.

75.       Melançon, P., Glick, B.S., Malhotra, V., Weidman, P.J., Serafini, T., Orci, L. , and Rothman, J.E.  1989.  A role for GTP‑binding proteins in vesicular transport through the Golgi complex.  In: Secretion and its Control (Chapter 11), Soc. Gen. Physiol. 44:175‑188.  Oxford , J.S. and Armstrong, C.M. (eds.), Rockefeller University Press, NY.

76.       Pfanner, N., Orci, L., Glick, B.S., Amherdt, M., Arden , S.R., Malhotra, V., and Rothman, J.E.  1989.  Fatty acyl‑coenzyme A is required for budding of transport vesicles from Golgi cisternae.  Cell  59:95‑102.

77.       Rothman, J.E.  1989.  Signal peptide recognition: GTP and methionine bristles.  Nature 340:433‑434.

78.       Rothman, J.E.  1989.  Polypeptide chain binding proteins: Catalysts of protein folding and related processes in cells.  Cell  59:591‑601.

79.       Rothman, J.E. and Orci, L.  1990.  A molecular dissection of vesicular transport. Chemtracts – Biochem. Molec. Biol.  1:89‑102.

80.       Pfanner, N., Glick, B.S., Arden , S.R., and Rothman, J.E.  1990.  Fatty acylation promotes fusion of transport vesicles with Golgi cisternae.  J. Cell Biol.  110:955‑961.

81.       Rothman, J.E. and Orci, L.  1990.  Movement of proteins through the Golgi stack: A molecular dissection of vesicular transport.  FASEB J.  4:1460‑1468.

82.       Clary, D.O. and Rothman, J.E.  1990.  Purification of three related peripheral membrane proteins needed for vesicular transport.  J. Biol. Chem.  265:10109‑10117.

83.       Clary, D.O., Griff, I.C., and Rothman, J.E.  1990.  SNAPS, a family of NSF attachment proteins involved in intracellular membrane fusion in animals and yeast.  Cell 61:709‑721.

84.       Rothman, J.E.  1990.  Protein folding and related processes in cells.  In: Proceedings of the Welch Foundation Conference on Chemical Research 33:53‑74.

85.       Helms, J.B., Karrenbauer, A., Wirtz, K.W., Rothman, J.E., and Wieland, F.T.  1990.  Reconstitution of steps in the constitutive secretory pathway in permeabilized cells.  Secretion of glycosylated tripeptide and truncated sphingomyelin.  J. Biol. Chem.  265:20027‑20032.

86.       Karrenbauer, A., Jeckel, D., Just, W., Birk, R., Schmidt, R.R., Rothman, J.E., and Wieland, F. T.  1990.  The rate of bulk flow from the Golgi to the plasma membrane.  Cell 63:259‑267.

87.       Rothman, J.E.  1990.  Phospholipid transfer market.  Nature 347:519‑520.  (Review)

88.       Waters, M.G., Serafini, T., and Rothman, J.E.  1991.  ‘Coatomer’: A cytosolic protein complex containing subunits of non‑clathrin-coated Golgi transport vesicles.  Nature 349:248‑251.

89.       Serafini, T., Stenbeck, G., Brecht, A., Lottspeich, F., Orci, L., Rothman, J.E., and Wieland, F.T.  1991.  A coat subunit of Golgi‑derived non‑clathrin‑coated vesicles with homology to the clathrin‑coated vesicle coat protein b‑adaptin.  Nature  349:215‑220.

90.       Rothman, J. E.  1991.  Enzymology of intracellular membrane fusion (Heinrich Wieland- Prize Lectures 1990).  Klinische Wochenschrift  69:98‑104.

91.       Orci, L., Tagaya, M., Amherdt, M., Perrelet, A., Donaldson, J.G., Lippincott‑Schwartz, J., Klausner, R.D., and Rothman, J.E.  1991.  Brefeldin A, a drug that blocks secretion, prevents the assembly of non‑clathrin-coated buds on Golgi cisternae.  Cell 64:1183-1195.

92.       Waters, M.G., Griff, I.C., and Rothman, J.E.   1991.  Proteins involved in vesicular transport and membrane fusion.  Curr. Opin. Cell Biol.  3:615-620.

93.       Wilson , D.W., Whiteheart, S.W., Orci, L., and Rothman, J.E.  1991.  Intracellular membrane fusion.  Trends Biochem. Sci.  16:334-337.

94.       Serafini, T., Orci, L., Amherdt, M., Brunner, M., Kahn, R.A., and Rothman, J.E.  1991.  ADP-ribosylation factor is a subunit of the coat of Golgi-derived COP-coated vesicles: A novel role for a GTP-binding protein.  Cell  67:239-253.

95.       Flynn, G.C., Pohl, J., Flocco, M.T., and Rothman, J.E.  1991.  Peptide-binding specificity of the molecular chaperone BiP.  Nature  353:726-730.

96.       Rothman, J.E.  1992.  The reconstitution of intracellular protein transport in cell-free systems.  The Harvey Lectures, Series 86:65-85.

97.       Rothman, J.E. and Orci, L.  1992.  Molecular dissection of the secretory pathway.  Nature 355:409-415. (Review)

98.       Bochkareva, E.S., Lissin , N.M. , Flynn, G.C., Rothman, J.E., and Girshovich, A.S.  1992.  Positive cooperativity in the functioning of molecular chaperone GroEL.  J. Biol. Chem. 267:6796-6800.

99.       Wilson , D. W., Whiteheart, S.W., Wiedmann, M., Brunner, M., and Rothman, J.E.  1992.  A multisubunit particle implicated in membrane fusion.  J. Cell Biol.  117:531-538.

100.     Whiteheart, S.W., Brunner, M., Wilson , D.W., Wiedmann, M., and Rothman, J.E.  1992.  Soluble N-ethylmaleimide-sensitive fusion attachment proteins (SNAPs) bind to a multi-SNAP receptor complex in Golgi membranes.  J. Biol. Chem.  267:12239-12243.

101.     Griff, I.C., Schekman, R., Rothman, J.E., and Kaiser , C.A.   1992.  The yeast SEC 17 gene product is functionally equivalent to mammalian a-SNAP protein.  J. Biol. Chem. 267:12106-12115.

102.     Waters, M.G., Clary, D.O., and Rothman, J.E.  1992.  A novel 115-kD peripheral membrane protein is required for intercisternal transport in the Golgi stack.  J. Cell Biol. 118:1015-1026.

103.     Rothman, J.E.  Golgi apparatus.  1992.  In: McGraw‑Hill Encyclopedia of Science and Technology, Seventh Edition, pp. 164-167.

104.     Rothman, J.E. (ed.)  1992.  Reconstitution of intracellular transport.  Meth. Enzymol.  219, Academic Press, New York .

105.     Helms, J.B. and Rothman, J.E.  1992.  Inhibition by brefeldin A of a Golgi membrane enzyme that catalyses exchange of guanine nucleotide bound to ARF.  Nature  360:352-354.

106.     Stenbeck, G., Schreiner, R., Herrmann, D., Auerbach, S., Lottspeich, F., Rothman, J.E., and Wieland, F.T.  1992.  g-COP, a coat subunit of non-clathrin-coated vesicles with homology to Sec21p.  FEBS Letters  314:195-198.

107.     Kahn, R.A., Randazzo, P., Serafini, T., Weiss, O., Rulka, C., Clark , J., Amherdt, M., Roller, P., Orci, L., and Rothman, J.E.  1992.  The amino terminus of ADP-ribosylation factor (ARF) is a critical determinant of ARF activities and is a potent and specific inhibitor of protein transport.  J. Biol. Chem. 267:13039-13046.

108.          Tagaya, M., Wilson , D.W., Brunner, M., Arango, N., and Rothman, J.E.  1993.  Domain structure of an N-ethylmaleimide-sensitive fusion protein involved in vesicular transport.  J. Biol. Chem. 268:2662-2666.

109.     Palmer, D.J., Helms, J.B., Beckers, C.J.M., Orci, L., and Rothman, J.E.  1993.  Binding of coatomer to Golgi membranes requires ADP-ribosylation factor.  J. Biol. Chem. 268:12083-12089.

110.     Park, K., Flynn, G.C., Rothman, J.E., and Fasman, G.D.  1993.  Conformational change of chaperone Hsc70 upon binding to a decapeptide:  A circular dichroism study.  Protein Science 2:325-330.

111.     Orci, L., Palmer, D.J., Ravazzola, M., Perrelet, A., Amherdt, M., and Rothman, J.E.  1993.  Budding from Golgi membranes requires the coatomer complex of non-clathrin coat proteins.  Nature 362:648-652.

112.          Helms, J.B., Palmer, D.J., and Rothman, J.E.  1993.  Two distinct populations of ARF bound to Golgi membranes.  J. Cell Biol. 121:751-760.  

113.     Orci, L., Palmer, D.J., Amherdt, M., and Rothman J.E.  1993.  Coated vesicle assembly in the Golgi requires only coatomer and ARF proteins from the cytosol.  Nature 364:732-734.

114.     Stamnes, M.A. and Rothman, J.E.  1993.  The binding of AP-1 clathrin adaptor particles to Golgi membranes requires ADP-ribosylation factor, a small GTP-binding protein.  Cell 73:999-1005.

115.     Söllner, T., Whiteheart, S.W., Brunner, M., Erdjument-Bromage, H., Geromanos, S., Tempst, P., and Rothman, J.E.  1993.  SNAP receptors implicated in vesicle targeting and fusion.  Nature 362:318-324.

116.     Whiteheart, S.W., Griff, I.C., Brunner, M., Clary, D.O., Mayer, T., Buhrow , S.A. , and Rothman, J.E.  1993.  SNAP family of NSF attachment proteins includes a brain-specific isoform.  Nature 362:353-355.

117.     Orci, L., Perrelet, A., Ravazzola, M., Wieland, F.T., Schekman, R., and Rothman, J.E.  1993.  “BFA bodies”:  A subcompartment of the endoplasmic reticulum.  Proc. Natl. Acad. Sci. USA 90:11089-11093.

118.     Söllner, T., Bennett, M.K., Whiteheart, S.W., Scheller, R.H., and Rothman, J.E.  1993.  A protein assembly-disassembly pathway in vitro that may correspond to sequential steps of synaptic vesicle docking, activation, and fusion. Cell 75:409-418.

119.     Tanigawa, G., Orci, L., Amherdt, M., Ravazzola, M., Helms, J.B., and Rothman, J.E.  1993.  Hydrolysis of bound GTP by ARF protein triggers uncoating of Golgi-derived COP-coated vesicles.  J. Cell Biol.  123:1365-1371.

120.     Ostermann, J., Orci, L., Tani, K., Amherdt, M., Ravazzola, M., Elazar, Z.., and Rothman, J.E.  1993.  Stepwise assembly of functionally active transport vesicles.  Cell 75:1015-1025.

121.     Kuge, O., Hara-Kuge, S., Orci, L., Ravazzola, M., Amherdt, M., Tanagawa, G., Wieland, F.T., and Rothman, J.E.  1993.  z-COP, a subunit of coatomer, is required for COP-coated vesicle assembly.  J. Cell Biol.  123:1727-1734.

122.          Hara-Kuge, S., Kuge, O., Orci, L., Amherdt, M., Ravazzola, M., Wieland, F.T., and Rothman, J.E.  1994.  En bloc incorporation of coatomer subunits during the assembly of COP-coated vesicles.  J. Cell Biol.  124:883-892.

123.     Elazar, Z., Mayer, T., and Rothman, J.E.  1994.  Removal of Rab GTP-binding proteins from Golgi membranes by GDP dissociation inhibitor inhibits inter-cisternal transport in the Golgi stacks.  J. Biol. Chem.  269:794-797.

124.     Elazar, Z., Orci, L., Ostermann, J., Amherdt, M., Tanigawa, G., and Rothman, J.E.  1994.  ADP-ribosylation factor and coatomer couple fusion to vesicle budding.  J. Cell Biol. 124:415-424.

125.     Rothman, J.E. and Warren , G.  1994.  Implications of the SNARE hypothesis for intracellular membrane topology and dynamics.  Curr. Biol.  4:220-233.

126.     Kuge, O., Dascher, C., Orci, L., Rowe, T., Amherdt, M., Plutner, H., Ravazzola, M., Tanigawa, G., Rothman, J.E., and Balch, W.E.  1994.  Sar1 promotes vesicle budding from the endoplasmic reticulum but not Golgi compartments.  J. Cell Biol.  125:51-65.

127.     Whiteheart, S.W., Rossnagel, K., Buhrow , S.A. , Brunner, M., Jaenicke, R., and Rothman, J.E.  1994.  N-ethylmaleimide-sensitive fusion protein: A trimeric ATPase whose hydrolysis of ATP is required for membrane fusion.  J. Cell Biol.  126:945-954.

128.     Söllner, T. and Rothman, J.E.  1994.  Neurotransmission:  Harnessing fusion machinery at the synapse.  Trends Neurosci.  17:344-348.

129.     Søgaard, M., Tani, K., Ye, R.R., Geromanos, S., Tempst, P., Kirchhausen, T., Rothman, J.E., and Söllner, T.  1994.  A Rab protein is required for the assembly of SNARE complexes in the docking of transport vesicles.  Cell 78:937-948.

130.     Rothman, J.E.  1994.  Mechanisms of intracellular protein transport.  Nature 372:55-63.

131.     Rothman, J.E.  1994.  Intracellular membrane fusion.  In: Molecular and Cellular Mechanisms of Neurotransmitter Release.  Stjärne, L., Greengard, P., Grillner, S., Hökfelt, T., and Ottoson, D. (eds.), Raven Press, NY, pp. 81-96.

132.     Orci, L., Perrelet, A., Ravazzola, M., Amherdt, M., Rothman, J.E., and Schekman, R.  1994.  Coatomer-rich endoplasmic reticulum.  Proc. Natl. Acad. Sci. USA 91:11924-11928. 

133.     DeBello, W.M., O’Connor, V., Dresbach, T., Whiteheart, S.W., Wang, S.S.-H, Schweizer, F.E., Betz, H., Rothman, J.E., and Augustine, G.J.  1995.  SNAP-mediated protein-protein interactions essential for neurotransmitter release.  Nature  373:626-630.

134.     Miesenböck, G. and Rothman, J.E.  1995.  The capacity to retrieve escaped ER proteins extends to the trans-most cisterna of the Golgi stack.  J. Cell Biol.  129:309-319.

135.          Stamnes, M.A., Craighead, M.W., Hoe, M.H., Lampen, N., Geromanos, S., Tempst, P., and Rothman, J.E.  1995.  An integral membrane component of coatomer-coated transport vesicles defines a family of proteins involved in budding.  Proc. Natl. Acad. Sci. USA  92:8011-8015.

136.     Schiavo, G., Gmachl, M.J.S., Stenbeck, G., Söllner, T.H., and Rothman, J.E.  1995.  A possible docking and fusion particle for synaptic transmission.  Nature  378:733-736.

137.     Rothman, J.E.  1996.  The protein machinery of vesicle budding and fusion.  Protein Science  5:185-194.

138.     Rothman, J.E. and Orci, L.  1996.  Budding vesicles in living cells.   Sci. Amer.  274:70-75.

139.     Nagahama, M., Orci, L., Ravazzola, M., Amherdt, M., Lacomis, L., Tempst, P., Rothman, J.E., and Söllner, T.H.  A v-SNARE implicated in intra-Golgi transport.  1996.  J. Cell Biol.  133:507-516.

140.     Rothman, J.E. and Wieland, F.T.  1996.  Protein sorting by transport vesicles.  Science 272:227-234.

141.     Veit, M., Söllner, T.H., and Rothman, J.E.  1996.  Multiple palmitoylation of synaptotagmin and the t-SNARE SNAP-25.  FEBS Lett.  385:119-123.

142.     Rothman, J.E.  1996.  Mechanisms of intracellular protein transport.  Felix Hoppe-Seyler Lecture 1996, Biol. Chem.  377:407-410.

143.     Fiedler, K., Veit, M., Stamnes, M.A., and Rothman, J.E.  1996.  Bimodal interaction of coatomer with the p24 family of putative cargo receptors.  Science  273:1396-1399.

144.          Schiavo, G., Gu, Q.M., Prestwich, G.D., Söllner, T.H., and Rothman, J.E.  1996.  Calcium-dependent switching of the specificity of phosphoinositide binding to synaptotagmin.  Proc. Natl. Acad. Sci. USA  93:13327-13332.

145.          Söllner, T.H. and Rothman, J.E.  1996.  Molecular machinery mediating vesicle budding, docking and fusion.  Experientia  52:1021-1025.

146.          Schiavo, G., Stenbeck, G., Rothman, J.E., and Söllner, T.H.  1997.  Binding of the synaptic vesicle v-SNARE, synaptotagmin, to the plasma membrane t-SNARE, SNAP-25, can explain docked vesicles at neurotoxin-treated synapses.  Proc. Natl. Acad. Sci. USA 94:997-1001.

147.     Miesenböck, G. and Rothman, J.E.  1997.  Patterns of synaptic activity in neural networks recorded by light emission from synaptolucins. Proc. Natl. Acad. Sci. USA  94:3402-3407. 

148.     Paek, I. , Orci, L., Ravazzola, M., Erdjument-Bromage, H., Amherdt, M., Tempst, P., Söllner, T.H., and Rothman, J.E.  1997.  ERS-24, a mammalian v-SNARE implicated in vesicle traffic between the ER and the Golgi.  J. Cell Biol.  137:1017-1028.

149.     McNew, J.A., Søgaard, M., Lampen , N.M. , Machida , S., Ye, R.R., Lacomis, L., Tempst, P., Rothman, J.E., and Söllner, T.H.  1997.  Ykt6p, a prenylated SNARE essential for endoplasmic reticulum-Golgi transport.  J. Biol. Chem.  272:17776-17783.

150.     Rothman, J.E., and Söllner, T.H.  1997.  Throttles and dampers:  Controlling the engine of membrane fusion.  Science  276:1212-1213.

151.     Orci, L., Stamnes, M., Ravazzola, M., Amherdt, M., Perrelet, A., Söllner, T.H., and Rothman, J.E.  1997.  Bidirectional transport by distinct populations of COPI-coated vesicles.  Cell  90:335-349.

152.     Fiedler, K. and Rothman, J.E.  1997.  Sorting determinants in the transmembrane domain of p24 proteins.   J. Biol. Chem.  272:24739-24742.

153.     Orci, L., Perrelet, A., and Rothman, J.E.  1998.  Vesicles on strings:  Morphological evidence for processive transport within the Golgi stack.  Proc. Natl. Acad. Sci. USA  95:2279-2283

154.     Weber, T., Zemelman, B.V., McNew, J.A., Westermann, B., Gmachl, M., Parlati, F., Söllner, T.H., and Rothman, J.E.  1998.  SNAREpins: Minimal machinery for membrane fusion.  Cell  92:759-772.

155.     Miesenböck, G., De Angelis, D.A., and Rothman, J.E.  1998.  Visualizing secretion and synaptic transmission with pH-sensitive green fluorescent proteins.  Nature 394:192-195.

156.     De Angelis, D.A., Miesenböck, G., Zemelman, B.V., and Rothman, J.E.  1998.  PRIM:  Proximity imaging of green fluorescent protein-tagged polypeptides.  Proc. Natl. Acad. Sci. USA  95:12312-12316.

157.     Stamnes, M., Schiavo, G., Stenbeck, G., Söllner, T.H., and Rothman, J.E.  1998.  ADP-ribosylation factor and phosphatidic acid levels in Golgi membranes during budding of coatomer-coated vesicles.   Proc. Natl. Acad. Sci. USA  95:13676-13680.

158.          Hohl, T.M., Parlati, F., Wimmer, C., Rothman, J.E., Söllner, T.H., and Engelhardt, H.  1998.  Arrangement of subunits in 20 S particles  consisting of NSF, SNAPs, and SNARE complexes.   Mol. Cell  2:539-548.

159.          Bremser, M., Nickel, W., Schweikert, M., Ravazzola, M., Amherdt, M., Hughes , C.A. , Söllner, T.H., Rothman, J.E., and Wieland, F.T.  1999.  Coupling of coat assembly and vesicle budding to packaging of putative cargo receptors.  Cell  96:495-506.

160.          McNew, J.A., Weber, T., Engelman, D.M., Söllner, T.H., and Rothman, J.E.  1999.  The length of the flexible SNAREpin juxtamembrane region is a critical determinant of SNARE-dependent fusion.  Mol. Cell  4:415-421.

161.          Parlati, F., Weber, T., McNew, J.A., Westermann, B., Söllner, T.H., and Rothman, J.E.  1999.  Rapid and efficient fusion of phospholipid vesicles by the a-helical core of a SNARE complex in the absence of an N-terminal regulatory domain.  Proc. Natl. Acad. Sci. USA  96:12565-12570.

162.          Nickel, W., Weber, T., McNew, J.A., Parlati, F., Söllner, T.H., and Rothman, J.E.  1999.  Content mixing and membrane integrity during membrane fusion driven by pairing of isolated v-SNAREs and t-SNAREs.  Proc. Natl. Acad. Sci. USA  96:12571-12576.

163.          Brügger, B., Nickel, W., Weber, T., Parlati, F., McNew, J.A., Rothman, J.E., and Söllner, T.   2000.   Putative fusogenic activity of NSF is restricted to a lipid mixture whose coalescence is also triggered by other factors.  EMBO J.  19:1272-1278.

164.          Rivera, V.M., Wang, X., Wardwell, S., Courage, N.L., Volchuk, A., Keenan, T., Holt, D.A., Gilman, M., Orci, L., Cerasoli Jr., F., Rothman, J.E., and Clackson, T.   2000.   Regulation of protein secretion through controlled aggregation in the endoplasmic reticulum.  Science  287:826-830.

165.          Moroi, Y., Mayhew, M.,  Trcka, J., Hoe, M.H., Takechi, Y., Hartl, F.U., Rothman, J.E., and Houghton, A.N.  2000.  Induction of cellular immunity by immunization with novel hybrid peptides complexed to heat shock protein 70.  Proc. Natl. Acad. Sci. USA  97:3485-3490.

166.          Castellino, F., Boucher, P.E., Eichelberg, K., Mayhew, M., Rothman, J.E., Houghton, A.N., and Germain, R.N.  2000.  Receptor-mediated uptake of antigen/heat shock protein complexes results in major histocompatibility complex class I antigen presentation via two distinct processing pathways.  J. Exp. Med.  191:1957-1964.

167.          Weber, T., Parlati, F., McNew, J.A., Johnston , R.J., Westermann, B., Söllner, T.H., and Rothman, J.E.  2000.  SNAREpins are functionally resistant to disruption by NSF and aSNAP.   J. Cell Biol.  149:1063-1072.

168.          McNew, J.A., Weber, T., Parlati, F., Johnston , R.J., Melia, T.J., Söllner, T.H., and Rothman, J.E.  2000.  Close is not enough: SNARE-dependent membrane fusion requires an active mechanism that transduces force to membrane anchors.   J. Cell Biol.  150:105-117.

169.          Volchuk, A., Amherdt, M., Ravazzola, M., Brügger, B., Rivera, V.M., Clackson, T., Perrelet, A., Söllner, T.H., Rothman, J.E., and Orci, L.  2000.  Megavesicles implicated in the rapid transport of intracisternal aggregates across the Golgi stack.  Cell 102:335-348.

170.          Sankaranarayanan, S., De Angelis, D., Rothman, J.E., and Ryan, T.A.  2000.  The use of pHluorins for optical measurements of presynaptic activity.  Biophys. J.  79:2199-2208.

171.          McNew, J.A., Parlati, F., Fukuda, R., Johnston , R.J., Paz, K., Paumet, F., Söllner, T.H., and Rothman, J.E.  2000.  Compartmental specificity of cellular membrane fusion encoded in SNARE proteins.  Nature  407:153-159.

172.          Parlati, F., McNew, J.A., Fukuda, R., Miller, R., Söllner, T.H., and Rothman, J.E.  2000.  Topological restriction of SNARE-dependent membrane fusion.  Nature  407:194-198.

173.          Fukuda, R., McNew, J.A., Weber, T., Parlati, F., Engel, T., Nickel, W., Rothman, J.E., and Söllner, T.H.  2000.  Functional architecture of an intracellular membrane t-SNARE.  Nature  407:198-202.

174.          Orci, L., Ravazzola, M., Volchuk, A., Engel, T., Gmachl, M., Amherdt, M., Perrelet, A., Söllner, T.H., and Rothman, J.E.  2000.  Anterograde flow of cargo across the Golgi stack potentially mediated via bidirectional “percolating” COPI vesicles.  Proc. Natl. Acad. Sci. USA  97:10400-10405.

175.          Orci, L., Amherdt, M., Ravazzola, M., Perrelet, A., and Rothman, J.E.  2000.  Exclusion of Golgi residents from transport  vesicles budding from Golgi cisternae in intact cells.  J. Cell Biol.  150:1263-1269.

176.          Pelham, H.R.B., and Rothman, J.E.  2000.  The debate about transport in the Golgi – Two sides of the same coin?  Cell  102:713-719.

177.          Wimmer, C., Hohl, T.M., Hughes , C.A. , Müller , S.A. , Söllner, T.H., Engel, A., and Rothman, J.E.  2001.  Molecular mass, stoichiometry, and assembly of 20 S particles.  J. Biol. Chem.  276:29091-29097.

178.          Rothman, J.E.  2001.  Great Experiments:  Protein Transport – The Cell-free Reconstitution of Vesicle Transport (http://www.ergito.com/servlet/Lookup?expt=rothman1)

179.          Rothman, J.E., and Söllner, T.H.  2001.  Great Experiments:  Protein Transport – The SNARE Complex and Its Role In the Specificity of Membrane Fusion (http://www.ergito.com/servlet/Lookup?expt=rothman2)

180.          Paumet, F., Brügger, B., Parlati, F., McNew, J.A., Söllner, T.H., and Rothman, J.E.  2001.  A t-SNARE of the endocytic pathway must be activated for fusion.  J. Cell Biol. 155:961-968.

181.          Parlati, F., Varlamov, O., Paz, K., McNew, J.A., Hurtado, D., Söllner, T.H., and Rothman, J.E. 2002.  Distinct SNARE complexes mediating membrane fusion in Golgi transport based on combinatorial specificity.  Proc. Natl. Acad. Sci. USA 99:54424-5429.

182.          Melia, T.E., Weber, T., McNew, J.A., Fisher, L.E., Johnston , R.J., Parlati, F., Mahal, L.K., Söllner, T.H., and Rothman, J.E.  2002 Regulation of membrane fusion by conformational switching of the membrane-proximal coil of the t-SNARE during zippering of SNAREpins.  J. Cell Biol. 158:929-940.

1 83.     Cosson, P., Amherdt, M., Rothman, J.E., and Orci, L.  2002.  A resident Golgi protein is            excluded from per-Golgi vesicles in NRK cells.  Proc. Natl. Acad. Sci. USA   99: 1 283 1 -       1 2834.

184.     Rothman, J.E.  2002.  Lasker Basic Medical Research Award.  The machinery and         principles of vesicle transport in the cell.  Nature Med.  8:1059-1062

185.     Hu, C., Ahmed, M., Melia, T.J., Söllner, T.H., Mayer, T., and Rothman, J.E.  2003.  Fusion        of cells by ‘flipped’ SNAREs.  Science 300: 1745-1749.

186.     Burri, L., Varlamov, O., Döge , C.A. Hofmann, K., Beilharz, T., Rothman, J.E., Söllner, T.H. and Lithgow, T.  2003.  A novel SNARE required for retrograde transport to the           endoplasmic reticulum.  Proc. Natl. Acad. Sci.  USA 100:9873-9877.

187.     Varmalov, O., Volchuk, A., Rahimian, V., Doege , C.A. , Paumet, F., Eng, W.E., Arango,        N., Parlati, F., Ravazzola, M., Orci, L., Söllner,T.H., and Rothman, J.E.  2004.

            i-SNAREs: inhibitory SNAREs that fine-tune the specificity of membrane fusion.  J. Cell            Biol. 164:79-88.

188.     Paumet, F., Rahimian, V. and James E. Rothman.  2004. The Specificity of SNARE-dependent fusion in encoded in the SNARE motif.  Proc. Natl. Acad. Sci. USA 101:3376-3380.

189.     Fix, M., Melia, T.J., Jaiswal, J.K. Rappoport, J.Z., You, D., Sollner, T.H., Rothman, J.E. and Simon, S.M.  2004.  Imaging single-membrane fusion events mediatd by SNARE proteins.  Proc. Natl. Acad. Sci. USA 101:7311-7316.

190.     Fukasawa, M., Varlamov, O., Eng, W.S., Söllner, T.S., Rothman, J.E.  2004. Localization and activity of the SNARE Ykt6 determined by its regulatory domain and palmitoylation. Proc. Natl. Acad. Sci. USA. 101: 4815-4820.

1 9 1 .     Volchuk, A., Ravazzola, M., Perrelet, A., Eng, W.S., Di Liberto, M., Varlamov, O., Fukasawa, M., Engel, T., Söllner, T.S., Rothman, J.E., Orci. L. 2004. Countercurrent Distribution of Two Distinct SNARE Complexes Mediating transport within the Golgi Stack. Mol. Biol. of the Cell 1 5: 1 506- 1 5 1 8.

192.     Becker, T., Volchuk, A., and Rothman, J.E.  2004.  Differential use of ER membrane for phagocytosos in J774 macrophages.  Proc. Natl. Acad. Sci.  USA . 102:4022-4026.

193.     Paumet, F, Rahimian, V., Di Liberto, M. and Rothman, J.E.  2005.  Concerted Auto-Regulation in Yeast Endosomal, t-SNAREs.  J. Biol. Chem. 280: 21137-21143.

194.     Giraudo, C.G., Hu, C., You, D., Slovic, A., Mosharov, E.V., Sulzer, D., Melia, T.J., Rothman, J.E. 2005. SNAREs Can Promote Complete Fusion and Hemifusion as Alternative Outcomes.   J.  Cell Biol. 170:249-280.

195.     Cosson, P., Ravazzola, M., Varlamov, O., Söllner, T.H., Di Liberto, M., Volchuk, A., Rothman, J.E., Orci, L. 2005.  Dynamic transport of SNARE proteins in the Golgi apparatus.  Biological Sciences.  Proc. Natl. Acad. Sci.  USA .  102:14647-14652.